IAAC-BASED SENOLYTICS
Chronic Kidney Disease Immunosenescence
Liver Fibrosis Pulmonary Fibrosis
Neurodegenerative Diseases Frailty
Sarcopenia Osteoarthritis
mRNA-BASED SENOLYTICS
Miscellaneous
Challenges: World population of 65+ is expected to double from 740 M (2020) to 1.6 B (2050)
~80 % of 65+ population suffers from at least one chronic condition
Rockfish Bio wins prestigious Science and Business Award 2025!
Rockfish Bio, a spin-off of BOKU and Medical University of Vienna, convinced the jury with its novel senolytic drug candidates, which specifically target and remove senescent cells — aged, dysfunctional cells that accumulate in tissues over time and contribute to chronic diseases. By leveraging a specific metabolic pathway found in these aged cells, Rockfish Bio's compounds eliminate them without harming healthy cells.
Preclinical studies have shown remarkable effects, including extension of both lifespan and healthspan and restoration of neuromuscular function, supporting the therapeutic potential of these compounds in promoting healthy aging and treating age-related conditions.
“We are honored to receive the S&B Award. This recognition is a great motivation and validation of our mission to develop effective therapies against aging-related diseases,” said Dr. Ingo Lämmermann, CSO/COO of Rockfish Bio.
First results from ongoing studies in preclinical disease models show best-in-class efficacy in stroke and chronic kidney disease!
Get in touch with us to learn more about our excellent PK data and the ongoing preclinical disease models...
Lead compound RFB01016 extends health and life span, improves neuromuscular function and reduces senescent cells in several tissues (kidney, liver, brain, spleen, fat, ...).
Epilipidomics of Senescent Dermal Fibroblasts Identify Lysophosphatidylcholines as Pleiotropic Senescence-Associated Secretory Phenotype (SASP) Factors
Startup Report
Longevity Senotherapeutics Report
Wie man mit 80 den Körper eines 30-Jährigen haben kann
Supported by:
HEALTHY AGING
office@rockfishbio.com
Rockfish Bio AG
Reichsratsstrasse 15/15
1010 Wien
Austria
FN 569591 i, HG Wien
UID/VAT: ATU77556949
